We cannot analyze endemic mycoses as we did just a few years ago. These fungal diseases have acquired much larger importance, and many have disseminated to novel areas of the globe. Immunosuppression has put additional patients at risk. Moreover, diagnosis has now been improved via antigen detection and/or molecular techniques, and innovations in treatment have also occurred. This reprint deals specifically with recent advances in the epidemiology, diagnosis, and treatment of endemic mycoses.

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Over the last few decades, nanomedicine has become a hot topic in formulation science regarding selectively delivering drugs to target tissues. Nanomedicines can modify drug release and encapsulate poorly soluble drugs, allowing for a selective targeting and minimizing adverse effects. This is of key importance in antitumoral and anti-infectious therapies, in which undesired drug release can lead to severe damage to healthy tissues. Moreover, they protect drugs from degradation, allowing for the the delivery of RNA. This reprint encompasses works describing the design, development and characterization of lipid nanomedicines, dendrimers and virus nanoparticles among others, as well as the evaluation of their toxicity and their anticancer and antifungal efficacy. Moreover, it analyzes the quality assessment of nanomedicines under clinical investigation.

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

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The following research articles provides insights into advanced fruit preservation and quality enhancement techniques. Mango Quality Enhancement: Studies show that treatments incorporating 1-methylcyclopropene (1-MCP) and melatonin significantly improve mango appearance, sugar content, and antioxidant activities, highlighting their potential to extend shelf life. Modified Atmosphere Packaging for Fresh-Cut Melons: Research demonstrates the effectiveness of passive modified atmospheres in extending the freshness of fresh-cut melons, especially non-climacteric types, by adjusting packaging perforation levels. Natural Coatings on Blueberries and Grapefruit: Investigations into various coatings reveal inconsistent effects on weight loss in blueberries. Additionally, studies on thymol vapors indicate a natural method for controlling post-harvest diseases in grapefruit, enhancing fruit longevity. Optimal Storage Conditions and Fungal Infection Management: Comprehensive reviews suggest optimal storage temperatures for different apple and pear cultivars and detail how Penicillium expansum affects apple quality, offering strategies for decay management. Quality Testing and Soil Treatments: Advances in hyperspectral imaging for non-destructive quality testing in citrus and the impact of anaerobic soil disinfestation on winter melon juice quality are explored, showing how agricultural practices influence fruit characteristics. Loquat Fruit Post-Harvest Handling: A review of loquat fruit post-harvest technology discusses storage methods to mitigate deterioration and preserve quality.

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Novel technologies are playing an important role in the development of crop and livestock farming and have the potential to be the key drivers of sustainable intensification of agricultural systems. In particular, new sensors are now available with reduced dimensions, reduced costs, and increased performances, which can be implemented and integrated in production systems, providing more data and eventually an increase in information. It is of great importance to support the digital transformation, precision agriculture, and smart farming, and to eventually allow a revolution in the way food is produced. In order to exploit these results, authoritative studies from the research world are still needed to support the development and implementation of new solutions and best practices. This Special Issue is aimed at bringing together recent developments related to novel sensors and their proved or potential applications in agriculture.

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We are facing a complicated public health issue in the form of global drug shortages, including antibiotics. Synthetic biology empowers the next generation of antibiotics development, bringing us into a new era.

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This compilation is a reprint of the Special Issue “Therapeutic drug monitoring and pharmacokinetics-based individualization of drug therapy” of the peer-reviewed journal Pharmaceutics (ISSN: 1999-4923). The primary aim of this Special Issue was to provide a platform for presenting the findings of research performed using novel computer software-based approaches for the pharmacokinetic interpretation of the results of therapeutic drug monitoring. The compilation involves nineteen research articles and five review papers published between 2022 and 2024. The areas covered include pharmacotherapy following organ transplant, the treatment of the severely or even critically ill using antiinfectives, precision oncology, mental illness, cystic fibrosis, anticoagulant therapy, the treatment of diabetes, and ophthalmology.

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